Tuesday, December 31, 2019

Antegren Case Study - 8261 Words

9-408-025 NOVEMBER 14, 2007 JOSHUA MARGOLIS THOMAS DELONG TERRY HEYMANN Antegren: A Beacon of Hope As Jim Mullen, CEO of Biogen Idec, drove into work on February 19, 2004, he considered both the tremendous hope and stiff challenge generated by the company the previous day. The company had announced its intention to submit an application to the U.S. Food and Drug Administration (FDA) seeking approval for Antegren, a drug that Biogen Idec was developing in partnership with Elan to treat multiple sclerosis (MS). While the patient community and investors greeted the news with excitement, Mullen knew that to fulfill the promise of Antegren, he would need to make a number of crucial decisions and the company would need to bring the drug to†¦show more content†¦This process could take months and typically required extensive lead time to schedule meetings and review data with insurers—data that had to be convincing. Early FDA approval would mean short-circuiting that whole methodical process, and it was unclear if this could be finalized before the drug was approved. Although all the signals from the FDA were positive, there was also the risk that the FDA, which itself had been going through a period of upheaval, would not approve Antegren. If this happened, the reputation risk to Antegren could be irreversible, even if it was approved at a later date after further trials. Mullen knew his responsibility was nothing short of transforming the promise of Antegren into reality. He had to determine how to get the drug made and accessible to patients, and he had to lead the company to execute—in record time—on those plans. Mullen knew Biogen Idec could fulfill the high hopes of patients and investors, and now his task was to lead the company to do so. Biogen Idec History2 Cambridge, Massachusetts-based Biogen was founded in 1978, in the early days of the biotechnology industry. The company’s underpinnings rested on a tradition of great lab science. The company was one of the first to develop recombinant proteins using genetic technology. Two of its co-founders, Phillip Sharp andShow MoreRelatedManagement and Teaching Note19520 Words   |  79 Pagesecch the case for learning case collections update 2007 Quarter 4 Visit the case search section of the ecch website at www.ecch.com to identify relevant cases from the ecch collection and view over 31,000 full text inspection copies. ecch provides a free monthly e-mail update service giving details of new cases from all sources. Visit www.ecch.com to subscribe. Economics, Politics and Business Environment 9-407-049 ALLIANZ AG: BECOMING A EUROPEAN COMPANY Lorsch, JW; Chernak, A Harvard

Monday, December 23, 2019

Essay on Hitler vs. Stalin - 859 Words

Stalin vs. Hitler If two men were to be tagged with having the most impact, good or bad, on twentieth century Europe the names Joseph Stalin and Adolph Hitler would ring loud and clear. Adolf Hitler and Joseph Stalin were the most recognizable and known totalitarian leaders in Europe. They both had a great impact on the worlds history. Adolf Hitler was the Fuhrer of the III Reich and a leader of the Nazi Party. He is to blame for the break out of the II World War and for the creation of an ideology which caused the holocaust and suffering of many nations. Stalin was a leader of the Soviet Union until 1953. He was the initiator of the Great Purges in 1937 and the collectivization which caused a huge amount of victims in his own†¦show more content†¦Stalins scheme looked differently because it started in a state which has already been authoritarian and had already been involved in it. He didnt have to win support of masses as Hitler did but had to eliminate his contenders and strengthen his position inside the party. The biggest difference in the twos method on becoming the central figure in their countries government was Hitlers was very short, and acted more on instinct to win over the respect of his country in a little over a year. While Stalins was more of a very strategic chess match, so he had to build his positions slowly and had to remove many contenders that would enable him in his goal. Then very carefully set up his last opposition for his crucial, checkmate. Both men were very influential people, both men were skilled users of propaganda, they could use their words t o twist and manipulate the minds of people into believing that what they were saying was the absolute truth. Using this power, they would use people as their individual puppets and wouldnt think twice as if it was morally right or wrong. Since their countries were still recovering from World War I it was easier for both men to gain support of the people, with their lies of a better life and the prosperity that was just ahead over the horizon. Restoring the power back into their countries was of great importance to both men. After World War I, Russia had 9,150,000 casualties and Germany hadShow MoreRelatedHitler Vs. Stalin : A Politically Influenced Era1289 Words   |  6 PagesBre Greene Mrs. Bartel English 9 16 April 2015 Hitler vs. Stalin The mid 1900s was a very politically influenced era. Many affairs were going on at this time, and many leaders were stepping up for their countries. Two leaders in particular were Adolf Hitler and Joseph Stalin. These two dictators made some of the biggest impacts in history. The impacts made were far from positive. They wiped out whole groups of people and civilizations in hopes to gain power for their country. These two combinedRead MoreEssay On World War816 Words   |  4 Pagesfamilies to cry their lives away over their losses. We have lost over 4,000 people, due to reasons such as disease, combat, and military training accidents. But, like all wars, there will be many upsetting casualties. War never changes. Curse you, Hitler! What an oaf. I was starting to get sick of hearing about the war every time I wake up. This war had lasted for four years and three months before it was finally called off. I’m ten now, going on eleven in December. So, here are some good things:Read MoreContexts of Metropolis and 19841295 Words   |  6 Pagesand the Nazi Party/Hitler Nationalism Socialist German Worker s Party, anti-Russian and very nationalistic Represented main force opposing socialist revolution 1924, Hitler attempted coup but imprisoned Mein Kampf written while Hitler was imprisoned May 1925 to October 1926, rise of Hitler coincides with making of Metropolis 1929, referendum for Law Against the Enslavement of the German People (halting reparations payments) wasn t passed, but attention and support of Hitler and the Nazis gainedRead MoreA War Does Not Require Weapons1567 Words   |  7 PagesWorld War One and World War Two, political leaders, states, and nations were fighting against each other with and without the usage of weapons. The ideology of great philosophers, and raising leaders, such as: Herbert Spencer, Leon Trotsky, Joseph Stalin, Great Britain, and Russia brought civil wars and battles during the small timeframe between world wars. Before we go into depth on the one 30-year war, we begin with the settings of this one-30 year war. In the beginning of the 19th century, EuropeanRead MoreWhy Germany Lost the World War Two946 Words   |  4 PagesWhy Germany Lost the World War 2 After WW I Germany had many economic and political problems that allowed Adolph Hitler to become ruler of Germany. After Hitler appointed himself chancellor he started rebuilding the German military. After years of no international response to breaking the Treaty of Versailles Germany attacked Poland. From 1939 to 1941 Germany had won many victories; however 1941 was a turning point in the war. By the end of 1941 Germany would continuously lose land to the alliesRead MoreThe Cold War And The Soviet War845 Words   |  4 Pagesartillery, it was a war between capitalism vs. communism, democracy vs. dictatorship. This War actually started when Stalin of the USSR had a conference during the end of WWII who promised the American president, FDR, that he would allow there to be elections, democratic elections, in the Eastern part of Europe which had the soviet dominance. But in the year of 1945, in the Potsdam conference, after the death of FDR, and during Truman s presidency, Stalin drew back on the promises he had previouslyRead MoreCompetition Is The Driving Factor Of Technological Innovations1440 Words   |  6 PagesTechnology Competition World War II: Atomic Bomb Race Germany and Japan both had WWII programs to build an atomic bomb. While German efforts are well documented in the Farm Hall transcripts, Japan s work and progress is still a guarded secret. Just after Hitler came to power in 1933, the Nuremberg Laws were passed forbidding employment in the civil service to anyone with Jewish backgrounds. This included the state-run universities. This caused many scientists to flee Germany among which was Einstein andRead MoreEnglish Creative Task : Holly Lowe, Microelectronics, Antibiotics, Laser Technology, The Smartphone And Nuclear Weapons1140 Words   |  5 Pagesthe rapid spread of terrorism, especially through social media propaganda. The events of the Salem Witch Trials, which are displayed through Arthur Miller’s play ‘The Crucible’, are largely based around the ideas of hysteria and the notion of good vs. evil. Hysteria plays a significant role, both in the play and throughout the actual event of the trials. The representation of the characters through their uncontrollable emotion of fear or irrational outbursts of anger or excitement display thisRead MoreGood Versus Evil and Democracy Versus Fascism1453 Words   |  6 Pagesresulted in the six year war. The united states became the strongest nation in the world, thus being named the â€Å"good war† due to the outcome of the â€Å"good vs. evil† war, economical status, military strength, women being put to work and the African Americans fighting part of war they were already in after the World war II ended. Good vs. evil and democracy vs. fascism were some of the ways the United States projected the war to Americans. Which lead to the contribution of the names for the war, known asRead MoreThe Olympic Games: Faster, Higher, Stronger1466 Words   |  6 Pagesoffered to host the games that year, four of which were under Nazi regime. (past Olympic host city election results, 2014) In the end, the IOC voted to let the games be held in none other than Berlin, Germany, three years before World War II. Adolf Hitler, who was in power at the time, saw an opportunity in the Olympic Games because of how much media attention they received. He used them as a medium to promote his government and Aryan superiority. He declared that there shall be no Black or Jewish

Sunday, December 15, 2019

Discission Free Essays

â€Å"Consent for Treatment† Please respond to the following: * Ms. Davis, a patient at XYZ facility, had a difficult time sleeping and was given something to put her sleep at approximately 3:00 a. m. We will write a custom essay sample on Discission or any similar topic only for you Order Now A form was given to Ms. Davis to sign for surgery while going in and out of sleep at approximately 7:00 a. m. following the sleep medication. Was this an express consent or implied consent? Explain your answer. As the head administrator of the facility, discuss what concerns you have and what would you do with the person who presented Ms. Davis with the consent. A minor with a gunshot wound was rushed to the emergency room. The parents had not arrived yet. After rushing the minor to surgery, the medical team realized consent for surgery had not been signed. Explain what kind of consent should be obtained. Speculate on how often this kind of consent is applied and discuss your thoughts. According to our lectures in week 6, lecture 1, an express consent is done in words, written or oral. An implied consent is apparent by the actions that demonstrate the patient has agreed to the treatment. Either way both types of consent require the person to know all the facts about their treatment. This would include what they were being treated for, what types of procedures they are doing or would like to do and the risks and benefits for the treatment. They must be completely aware of what they are consenting to. In the above situation I would say that the type of consent they are seeking is the implied consent because they are trying to get the patient to sign a consent form for surgery. However she is, in my opinion not able to comprehend the facts of what she is consenting to because she is dosing off and on because of a sleeping aid she was given. She is under the influence of a medication that can have an affect of not also the obvious, sleepiness, but not really being able to comprehend their surroundings. People have a different reaction to medication therefore I cannot even fathom that even if they were able to get her to sign the consent form it should not hold up or be considered legal and standing because of the fact she was under the influence of a medication. It does not state that the surgery was an emergency in which if a surgery was a life-or-death situation where the consent was not needed. If I was the head Administrator of this facility, I would not allow this. The staff member who presented the patient with the consent under such circumstances would be reprimanded if not suspended for the lack of good judgment and lack of following policies and procedures of what is acceptable and legal for a consent to do surgery. I would not allow the patient to be put through the surgery because she, in my observation was not able to fully comprehend and understand what she was being asked to sign. According to our text it states â€Å"that an emergency eliminates the need to obtain consent because the law values the preservation of life and prevention of permanent impairment. However, this rule applies only when the patient is incapable of expressing consent and the healthcare surrogate is unavailable. The above situation states that the parents have not arrived therefore they do know what has happened to their child and with a gun shot wound the medical faculty made a choice to put the minor in an emergency surgery due to a gun shot wound Showalter, J. S. (2012). The Law of Healthcare Administration, 6th edition. Chicago, Illinois. Health Administration Press â€Å"A Tax-Free Health Care Organization† Please respond to the following: * Memorial Today Hospital is a teaching institution that provides community benefits and charity services to a large population of indigents in exchange for a tax-exemption status. Explain how the Health Reform Law of 2011 could impact the health care organization and its tax exemption status if it remains law. * Explain under what circumstances Memorial Today Hospital will be subject to income taxation. Discuss what this means to you as the administrator of the facility The 2011 Health Reform Law can impact the Memorial Today Hospital because it adds new requirements to the tax code and adds new standards regarding the care of the poor (Showalter, 2012). Now there must be a community health needs assessment conducted once every three years, an adoption and implementation of a strategy to meet health needs identified in the assessment, a written financial assistance policy must be publicized and implemented-essentially a charity care policy for services to indigent patients, adoption of a written policy on nondiscrimination in emergency services, limit the amounts charged for care to indigent patients, and non attempt â€Å" extraordinary collection actions† without first determining whether the patient meets financial assistance criteria. Memorial Today Hospital may be subject to income taxation if a charity earns revenue from a line of business that does not further its charitable purpose, that income is subject to unrelated business income taxation (UBIT) as though it were earned by a for-profit organization (Showalter, 2012). If I were the administrator of the facility, I would ensure I was working along with other non-profit companies for business that is not provided by the hospital setting. Showalter, J. S. (2012). The Law of Healthcare Administration, 6th edition. Chicago, Illinois. Health Administration Press How to cite Discission, Papers

Saturday, December 7, 2019

A Discussion of Assessment and Feedback Issues free essay sample

A discussion of assessment and feedback issues Assessment is an important part of teaching and learning, the most obvious reason for carrying out assessment is to evaluate the students learning/achievement s and whether the student is heading toward the course of qualification. Teaching within NVQ the criteria is laid out for me as a teacher my role is to prepare the students to observe their performances, question them, and use assessment to make a decision as to whether my learners are competent or capable. I must also to ensure that the assessment meets the criteria and objectives of the NVQ qualification. We as the teachers/assessors want to know whether learning outcomes have been achieved, or if the student is of a standard required to pass and achieve the grade /qualification. It also helps me as the tutor up most to help determine the development the student needs during the course. Assessment is also a away to provide information on individual teacher or the institution. For example; are the teaching methods affective, are the learning objectives appropriate- are they too easy or to difficult. Assessment within my teaching domain comprises of different components, performances in the work places, the use of realistic working environment. With NVQ teaching we have specific criteria that must be covered and include skills as well as knowledge, we the assessors have the decision as to how and where the assessment takes place. NVQ level 1-2-3 hairdressing comprises of units which must be cover die, Level 3 consists of 53 credits minimum split into mandatory units -48 credits and optional unit of which is 6 credits to pass and obtain the qualification. Following VTCT/HABIA critia guide lines and assessment work book. VTCT/HABIA strongly advocates a holistic approach for assessment of learners. Examples include using one assessment method to gather evidence for a number of criteria integrating knowledge into practical observation (i. e. through oral or evidenced on analysis sheets i. e. consultation forms). I myself as a teacher of hair and beauty believe in Habia and VTCT Assessment learning and teaching strategies I believe in engaging and exciting the learner whether it means I need to change the way I assess or how I bring my knowledge forward for learners to understand and help them complete their course. I measure the achievements against the standards set out. One of the advantages of NVQs is that the whole area to be tested is set out from the start. NVQ assessment is usually internal or external or a combination of the two. Internal assessment means myself is responsible for devising and marking assessments be it using case study’s which also help develop functional/key skills, observation ,oral ,informal,ect. These then tend to be verified by the centre internal verifier. I myself am required to set work that will improve practical skills knowledge and understanding. It’s my responsibility to guide learners on the evidence that is needed to be gathered to satisfy assessment. Within my course criteria (NVQ) we use formative and summative assessment as the main hold of the course. Unlike summative assessment which relates to assessment of learning, feedback relates to assessment for learning. Assessment 1998: Torrance and Pryor 1998) which helps the learners progress (Black and William We use formative assessment as formal or informal. For assessment to function formatively, the results have to be used to adjust teaching and learning. † (Black and William 1998: pp. -16) With formative assessment we use a range of activitys, case studies, multiple choice test, practical test, projects, questioning alone or within a group. To help students understand the frame work and what is needed we use in NVQ or within my institution mile stones of 13 weeks covering formative summative and mandatory test assessment. I strongly believe in formative a ssessment for the students and me the teacher for my own evaluation as well as theses; it contributes to the learner’s progress provided guidance on how to bridge the gaps to achieve the desired results, we use ILPS to also help within this process. ILPs individual learning plans, we use these to encourage the students also for means of developing their own targets and to motivate and encourage the students learning development. These documents are updated by learner and teacher throughout the course and are used as part of the formal course assessment. Summative assessment is used for grading or within my teaching domain it’s a simple pass or fail. As stated in (Teaching skills in the further and adult education 3rd addition David Minton p 288) progression and new technology. There is no reason why a teaching session in a hairdressing salon should not be video-taped or photo graphed and presented with by the teacher to explain whys/he did what, what happened, what was observed in a group or individual work. It’s a valuable tool for evaluation as well as valid evidence. It can be shared with mentor or other tutor to compare and evaluate work, to review Atcual teaching session also and assessment of students. I myself have used this and found it a good tool to be used. In regards to questions and feed back during assessment, It’s important to be specific on what can be improved and how. Effective feedback tells the student what they have achieved and where they need to improve. Questioning is used not only as a pedagogical tool but also as a deliberate way for myself the teacher to find out what knowledge and understanding the leaner’s have gained, also to helps myself the teacher see how successful my teaching has been and what areas need to be improved . Questioning is fundamental to effective teaching and learning. As stated by ( Fisher amp; Frey 2007) Checking for understanding through questioning should not be thought as a simple two step process but rather as a complex progression as the teacher formulates and then listens to the responses of the learners, IE making them from easy to hard and simplifying them for students own level of learning. Self and peer assessment can also be beneficial in feedback and evaluation on own and peers works. As state many academic teachers still tend to retain all ownership and power in the assessment process (Dorothy spiller teaching development wahonga Feb 2012 assessment matters). Self assessment is used during formative assessment which students reflects and evaluates their own work. Seeing their strengths weaknesses and areas they feel they need to improve, helps set self goals becoming more motivated. Self assessment within my teaching area requires the student to fill out self assessment feedback forms in relation to a practical activities carried out, this help them self –evaluate their work strengths and weaknesses. â€Å"SELF ASSESMENT WITH ITS EMPHASIS ON STUDENT RESPONAIBITIY AND MAKING JUDGMENT IS NECESSARY SKILL FOR LIFE LONG LEARNING â€Å"(Bond, 1995, P. 11,). In the3 same contexts Peer feedback can also be beneficial to individuals or groups of students who are keen to experiment and use new ideas. Peers assessment involving students giving feedback on peers work can help students make sense of gaps in their own work. I see self and peer assessment beneficial where certain points are present. Designed to enhance learning ,involving learners in judging own work, help improve and motivated owns mind and work . Boud, D (1995). Enhancing learning through self-assesment. London:Koger page. Boud, (1995 P. 11. ). (Black and William 1998: pp. 5-16) Douglas Fisheramp; Nancy Frey 2007 www. reading,org questioning. (Teaching skills in the further and adult education 3rd addition David Minton p 288)